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List of substances for condition Group: Thyroid

All Human Animal Risk/Association ReviewRows: 147

Substance InfoDose WarnLink PubMed
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Selenium 📋38714999Supplementation with selenium and coenzyme Q10 in an elderly Swedish population low in selenium - positive effects on thyroid hormones, cardiovascular mortality, and quality of life
Vitamin D3 📋38542128Autoimmune Thyroiditis and Vitamin D
Curcumin 📋37724034Curcumin exerts protective effects on the thyroid gland in propylthiouracil-treated rats
Vitamin C 📋37246589The interplay between vitamin C and thyroid
Metformin 📋37969194Metformin ameliorates insulin resistance, thyroid nodules and thyroid function
Melatonin 📋38730600Protective Effects of Melatonin against Carcinogen-Induced Oxidative Damage in the Thyroid
Vitamin E 📋38534308Vitamin E intake and prevalence rates of thyroid dysfunction and autoimmune thyroiditis: A cross-sectional analysis of NHANES data
Resveratrol 📋36470120Resveratrol thyro-protective role in fluorosis rat model (histo-morphometric, biochemical and ultrastructural study)
Nigella Sativa 📋37371976The Impact of Nigella sativa Essential Oil on T Cells in Women with Hashimoto's Thyroiditis
Prunella Vulgaris 📋37115092Investigation of the mechanism of Prunella vulgaris in treatment of papillary thyroid carcinoma based on network pharmacology integrated molecular docking and experimental verification
Quercetin 📋36510497To Explore the Inhibitory Mechanism of Quercetin in Thyroid Papillary Carcinoma through Network Pharmacology and Experiments
Iodine 📋37800143Iodine-induced thyroid dysfunction: a scientometric study and visualization analysis
Vitamin B8 📋36465640Supplementation with myo-inositol and Selenium improves the clinical conditions and biochemical features of women with or at risk for subclinical hypothyroidism
Thymoquinone 📋 36506574Thymoquinone protects the testes of hypothyroid rats by suppressing pro-inflammatory cytokines and oxidative stress and promoting SIRT1 testicular expression
Zinc 📋36749549Interaction Between Dietary Selenium and Zinc Intakes on Hypothyroidism
Food 📋 38370054Evaluation of the effect of gluten-free diet and Mediterranean diet on autoimmune system in patients with Hashimoto's thyroiditis
Ashwagandha 📋31958022Neuroprotective Effect of Ashwagandha Extract against the Neurochemical Changes Induced in Rat Model of Hypothyroidism
Berberine 📋37397788Antitumor Activity of Berberine by Activating Autophagy and Apoptosis in CAL-62 and BHT-101 Anaplastic Thyroid Carcinoma Cell Lines
EGCG 📋35599263The effects of Epigallocatechin-3-gallate and Dabrafenib combination on apoptosis and the genes involved in epigenetic events in anaplastic thyroid cancer cells
Genistein 📋29516914The Effects of Thymoquinone and Genistein Treatment on Telomerase Activity, Apoptosis, Angiogenesis, and Survival in Thyroid Cancer Cell Lines
L-Carnitine 📋15803480Muscle carnitine in hypo- and hyperthyroidism
Micronutrients 📋 37764737Autoimmune Thyroid Disorders: The Mediterranean Diet as a Protective Choice
Phytochemicals 📋 38674046Promising Approaches in Plant-Based Therapies for Thyroid Cancer: An Overview of In Vitro, In Vivo, and Clinical Trial Studies
Vitamin A 📋36303869The relationship between thyroid disorders and vitamin A.: A narrative minireview
Apigenin 📋37437745The effect of Apigenin on Glycometabolism and cell death in an anaplastic thyroid cancer cell line
Crocin 📋37982317Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy
Ginsenosides 📋35154537Ginsenoside Rh2 inhibits thyroid cancer cell migration and proliferation via activation of miR-524-5p
Hesperidin 📋37371665Hesperidin Attenuates Hypothyroidism-Induced Lung Damage in Adult Albino Rats by Modulating Oxidative Stress, Nuclear Factor Kappa-B Pathway, Proliferating Cell Nuclear Antigen and Inflammatory Cytokines
Lipoic Acid 📋36404819Metformin and alpha lipoic acid ameliorate hypothyroidism and its complications in adult male rats
Magnesium 📋36264466Associations of metal profiles in blood with thyroiditis: a cross-sectional study
Cannabidiol 📋35872737Cannabidiol improves thyroid function via modulating vitamin D 3 receptor in vitamin D 3 deficiency diet-induced rat model
Chrysin 📋34700210Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system
DHEA 📋33245519Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism
Emodin 📋 37927413Emodin treatment of papillary thyroid cancer cell lines in vitro inhibits proliferation and enhances apoptosis via downregulation of NF‑κB and its upstream TLR4 signaling
Gallic Acid 📋 36314079The molecular evaluation of thioredoxin (TXN1 & TXN2), thioredoxin reductase 1 (TXNRd1), and oxidative stress markers in a binary rat model of hypo- and hyperthyroidism after treatment with gallic acid
Iron 📋38004184Relationship between Iron Deficiency and Thyroid Function: A Systematic Review and Meta-Analysis
Luteolin 📋31966836Luteolin suppresses tumor progression through lncRNA BANCR and its downstream TSHR/CCND1 signaling in thyroid carcinoma
Minerals 📋 37711890Thyroid hormones and minerals in immunocorrection of disorders in autoimmune thyroid diseases
N-Acetyl Cysteine 📋32264788N-Acetylcysteine and Safranal Prevented the Brain Damage Induced by Hyperthyroidism in Adult Male Rats
Taurine 📋27562511Taurine Ameliorated Thyroid Function in Rats Co-Administered With Chlorpyrifos and Lead
Vitamin B12 📋35761487Correlation between Vitamin B12 Deficiency and Autoimmune Thyroid Diseases
Vitamin B9 📋34562187Folic acid attenuated learning and memory impairment via inhibition of oxidative damage and acetylcholinesterase activity in hypothyroid rats
Antioxidants 📋 35620378A Systematic Review on the Role of Antioxidants in Thyroid Eye Disease
Biochanin A 📋 20003293Effects of Dietary Phytoestrogens on Plasma Testosterone and Triiodothyronine (T3) Levels in Male Goat Kids
Capsaicin 📋35076979Capsaicin inhibits the stemness of anaplastic thyroid carcinoma cells by triggering autophagy-lysosome mediated OCT4A degradation
Coffee 📋37351106Effect of coffee consumption on thyroid function: NHANES 2007-2012 and Mendelian randomization
Daidzein 📋20003293Effects of Dietary Phytoestrogens on Plasma Testosterone and Triiodothyronine (T3) Levels in Male Goat Kids
Dioscin 📋 37551407Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling
Diosgenin 📋 35140607Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation
Ellagic Acid 📋36773307Ellagic acid inhibits cell proliferation, migration, and invasion of anaplastic thyroid cancer cells via the Wnt/β-catenin and PI3K/Akt pathways
Fish Oil 📋35712237Fish and the Thyroid: A Janus Bifrons Relationship Caused by Pollutants and the Omega-3 Polyunsaturated Fatty Acids
Frankincense 📋31322200Treatment for benign thyroid nodules with a combination of natural extracts
Green Tea Polyphenols 📋34018174Green tea extract modulates lithium-induced thyroid follicular cell damage in rats
Medicinal Plants 📋 37013429Achievements in Hypothyroidism Treatment with Herbal Medicine: A Systematic Review of Randomized Controlled Trials
Moringa Oleifera 📋34449175Efficacy and safety of Barg-e-Sahajna ( Moringa oleifera Lam.) in primary hypothyroidism
Naringin 📋37196197Implication of Wnt/GSK-3β/β-Catenin Signaling in the Pathogenesis of Mood Disturbances Associated with Hyperthyroidism in Rats: Potential Therapeutic Effect of Naringin
Neferine 📋 35794985Neferine Exerts Ferroptosis-Inducing Effect and Antitumor Effect on Thyroid Cancer through Nrf2/HO-1/NQO1 Inhibition
Nobiletin 📋 31287730Nobiletin Alone or in Combination with Cisplatin Decreases the Viability of Anaplastic Thyroid Cancer Cell Lines
Omega-3 Fatty Acids 📋35712237Fish and the Thyroid: A Janus Bifrons Relationship Caused by Pollutants and the Omega-3 Polyunsaturated Fatty Acids
Parthenolide 📋 37095470Untargeted lipidomic analysis and network pharmacology for parthenolide treated papillary thyroid carcinoma cells
Piperlongumine 📋 37175755Piperlongumine Induces Cellular Apoptosis and Autophagy via the ROS/Akt Signaling Pathway in Human Follicular Thyroid Cancer Cells
Probiotics 📋36275023Efficacy evaluation of probiotics combined with prebiotics in patients with clinical hypothyroidism complicated with small intestinal bacterial overgrowth during the second trimester of pregnancy
Puerarin 📋38668725Puerarin Alleviates Experimental Autoimmune Thyroiditis by Regulating Macrophages
Punicalagin 📋29677534Punicalagin induces senescent growth arrest in human papillary thyroid carcinoma BCPAP cells via NF-κB signaling pathway
Rapamycin 📋 36580373Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes
Salidroside 📋 36364314Antihypothyroid Effect of Salidroside
Silibinin 📋 37855349Network Pharmacological Analysis and Experimental Validation of the Effects of Silybin on Proliferation, Migration, and Immunotherapy of Papillary Thyroid Cancer
Acetyl-L-Carnitine 📋38460232Exploring the potential anti-thyroid activity of Acetyl-L-carnitine: Lactoperoxidase inhibition profile, iodine complexation and scavenging power against H2O2. Experimental and theoretical studies
Alfalfa 📋 11815400Phytoestrogens and Thyroid Cancer Risk: The San Francisco Bay Area Thyroid Cancer Study
Allicin 📋29545880Allicin Activates Autophagic Cell Death to Alleviate the Malignant Development of Thyroid Cancer
Apple Polyphenols 📋 35222800Effects of Annurca Flesh Apple Polyphenols in Human Thyroid Cancer Cell Lines
Artemisinin 📋 37036874Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway
Asiaticoside 📋 38044598Asiaticoside Down-Regulates HIF-1α to Inhibit Proliferation, Migration, and Angiogenesis in Thyroid Cancer Cells
Astragalosides 📋29127443Astragaloside IV attenuates orbital inflammation in Graves' orbitopathy through suppression of autophagy
Baicalein 📋31312348Baicalein induced apoptosis and autophagy of undifferentiated thyroid cancer cells by the ERK/PI3K/Akt pathway
Baicalin 📋32776035High-throughput metabolomic method based on liquid chromatography: high resolution mass spectrometry with chemometrics for metabolic biomarkers and pathway analysis to reveal the protective effects of baicalin on thyroid cancer
Beta-Carotene 📋9179066Selected micronutrient intake and thyroid carcinoma risk
Boric Acid 📋38689139In Vitro Effects of Boric Acid on Cell Cycle, Apoptosis, and miRNAs in Medullary Thyroid Cancer Cells
Calycosin 📋 36588732Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells
Cardamom 📋37403247Effect of Elettaria cardamomum L. on hormonal changes and spermatogenesis in the propylthiouracil-induced hypothyroidism male BALB/c mice
Cat's Claw 📋20032400Antiproliferative and pro-apoptotic effects of Uncaria tomentosa in human medullary thyroid carcinoma cells
Chamomile 📋31948119Both Matricaria chamomilla and Metformin Extract Improved the Function and Histological Structure of Thyroid Gland in Polycystic Ovary Syndrome Rats through Antioxidant Mechanism
Chlorella 📋32957734Chlorella sorokiniana Dietary Supplementation Increases Antioxidant Capacities and Reduces Ros Release in Mitochondria of Hyperthyroid Rat Liver
Citicoline 📋25589288Cardioprotective properties of citicoline against hyperthyroidism-induced reperfusion damage in rat hearts
CoQ10 📋38714999Supplementation with selenium and coenzyme Q10 in an elderly Swedish population low in selenium - positive effects on thyroid hormones, cardiovascular mortality, and quality of life
Cordyceps 📋34029950Cordyceps sinensis-derived fungus Isaria felina ameliorates experimental autoimmune thyroiditis in mice
Costus 📋38253277Metabolomic insights into the therapeutic mechanisms of costus (Saussurea costus (Falc.) Lipsch.) root extract in propylthiouracil-induced hypothyroidism rat model
D-Mannose 📋34886901ZIP10 is a negative determinant for anti-tumor effect of mannose in thyroid cancer by activating phosphate mannose isomerase
Dandelion 📋34219514Taraxasterol inhibits TGF-β1-induced epithelial-to-mesenchymal transition in papillary thyroid cancer cells through regulating the Wnt/β-catenin signaling
Diallyl Trisulfide 📋 33751676Diallyl trisulphide, a H 2 S donor, compromises the stem cell phenotype and restores thyroid-specific gene expression in anaplastic thyroid carcinoma cells by targeting AKT-SOX2 axis
Dihydroartemisinin 📋 35663306Dihydroartemisinin Exerts Antifibrotic and Anti-Inflammatory Effects in Graves' Ophthalmopathy by Targeting Orbital Fibroblasts
Echinacea 📋36613632Ameliorative Effect of Ethanolic Echinacea purpurea against Hyperthyroidism-Induced Oxidative Stress via AMRK and PPAR Signal Pathway Using Transcriptomics and Network Pharmacology Analysis
Escin 📋28378396The positive clinical therapeutically effects of Escin on advanced thyroid cancer
Eugenol 📋 35822681Eugenol: A New Option in Combination Therapy with Sorafenib for the Treatment of Undifferentiated Thyroid Cancer
Fenugreek 📋14692727The Combined Effects of Trigonella and Allium Extracts in the Regulation of Hyperthyroidism in Rats
Ferulic Acid 📋38637405Ameliorative effect of ferulic acid on thyroid dysfunction against propyl-thiouracil induced hypothyroid rats
Fish 📋 35712237Fish and the Thyroid: A Janus Bifrons Relationship Caused by Pollutants and the Omega-3 Polyunsaturated Fatty Acids
Folate 📋37563586Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus
Fucoidan 📋28447753Antitumor activity of fucoidan in anaplastic thyroid cancer via apoptosis and anti-angiogenesis
Fucoxanthin 📋32691210Effect of Fucoxanthin Administration on Thyroid Gland Injury Induced by Cadmium in Mice
Ginger 📋35096113Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Ginger extract 📋31757552Ginger Extract Ameliorates Bisphenol A (BPA)-induced Disruption in Thyroid Hormones Synthesis and Metabolism: Involvement of Nrf-2/HO-1 Pathway
Ginkgo Biloba 📋17711926Anticlastogenic effect of Ginkgo biloba extract in Graves' disease patients receiving radioiodine therapy
Grape 📋 31912105Red grape juice protects the rat thyroid gland against hypercholesterolemic changes. Ultrastructural and biochemical evidences
Grape Seed extract 📋32166689Renal protective effects of grape seed extract treatment against Eltroxin-induced hyperthyroidism, kidney damage, and oxidative stress in male mice
Hesperetin 📋 32657124Citrus flavanones upregulate thyrotroph Sirt1 and differently affect thyroid Nrf2 expressions in old-aged Wistar rats
Holy Basil 📋9721597Ocimum Sanctum Leaf Extract in the Regulation of Thyroid Function in the Male Mouse
Honokiol 📋 38659261Honokiol Suppresses Cell Proliferation and Tumor Migration through ROS in Human Anaplastic Thyroid Cancer Cells
Hypericin 📋 34454929Anti-cancer impact of Hypericin in B-CPAP cells: Extrinsic caspase dependent apoptosis induction and metastasis obstruction
Kaempferol 📋34690752Network Pharmacology to Explore the Molecular Mechanisms of Prunella vulgaris for Treating Hashimoto's Thyroiditis
Lemon Balm 📋38303002Melissa officinalis extract palliates redox imbalance and inflammation associated with hyperthyroidism-induced liver damage by regulating Nrf-2/ Keap-1 gene expression in γ-irradiated rats
Lutein 📋37207866Lutein Targeting orbital fibroblasts attenuates fibrotic and inflammatory effects in thyroid-associated ophthalmopathy
Lycopene 📋37125846The possible ameliorative role of Lycopene on Tributyltin induced thyroid damage in adult male albino rats (histological, immunohistochemical and biochemical study)
Modified Citrus Pectin 📋27551476Inhibition of malignant thyroid carcinoma cell proliferation by Ras and galectin-3 inhibitors
Myrtle Essential Oil 📋33015880Effect of myrtle (Myrtus communis L.) essential oil on oxidant-antioxidant balance in rats with propylthiouracil-induced hypothyroidism
Naringenin 📋32657124Citrus flavanones upregulate thyrotroph Sirt1 and differently affect thyroid Nrf2 expressions in old-aged Wistar rats
Oleuropein 📋 29715755Oleuropein and hydroxytyrosol protect rats' pups against bisphenol A induced hypothyroidism
Olive Oil 📋33561976Thyroid-Modulating Activities of Olive and Its Polyphenols: A Systematic Review
Olive Polyphenols 📋 33561976Thyroid-Modulating Activities of Olive and Its Polyphenols: A Systematic Review
Ollive Leaf extract 📋33561976Thyroid-Modulating Activities of Olive and Its Polyphenols: A Systematic Review
Onion 📋14692727The Combined Effects of Trigonella and Allium Extracts in the Regulation of Hyperthyroidism in Rats
Orange 📋 18598183Medicinal values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin, and thyroid hormones
Parsley 📋 34497857Antioxidant Potential of Parsley Leaf ( Petroselinum crispum) Essential Oil on Hypothyroidism and Testicular Injury in Mice Intoxicated by Carbon Tetrachloride
Phytoestrogens 📋 11815400Phytoestrogens and Thyroid Cancer Risk: The San Francisco Bay Area Thyroid Cancer Study
Pine Bark 📋31099529Pycnogenol® Prevents Oxidative Stress and Side Effects in Patients With Hypothyroidism During Levothyroxine Treatment
Piperine 📋30935902Effects of Curcumin and Its Adjuvant on TPC1 Thyroid Cell Line
Polydatin 📋 31705858Polydatin attenuates orbital oxidative stress in Graves' orbitopathy through the NRF2 pathway
Polyphenols 📋 35571253The Cross-Talk between Polyphenols and the Target Enzymes Related to Oxidative Stress-Induced Thyroid Cancer
Pomegranate Peel extract 📋36370004Pomegranate (Punica granatum) peel alleviates lithium-induced alterations in the thyroid gland of rats by modulating apoptosis and oxidative stress
PQQ 📋38095308The Potential Role of Pyrroloquinoline Quinone to Regulate Thyroid Function and Gut Microbiota Composition of Graves' Disease in Mice
Prebiotics 📋36275023Efficacy evaluation of probiotics combined with prebiotics in patients with clinical hypothyroidism complicated with small intestinal bacterial overgrowth during the second trimester of pregnancy
Pumpkin Seed 📋33504684Anti-proliferative and apoptotic effects of hull-less pumpkin extract on human papillary thyroid carcinoma cell line
Safranal 📋 32264788N-Acetylcysteine and Safranal Prevented the Brain Damage Induced by Hyperthyroidism in Adult Male Rats
Salt 📋 34084229The effect of salt supplements on thyroid hormones and quality of pregnancy in female hypothyroid rats
Schisandra 📋32802128Evaluation of the Effects of Schisandra chinensis on the Myocardium of Rats with Hyperthyroid Heart Disease by Using Velocity Vector Imaging Combined with the Estimation of p53 Expression and Calmodulin Activity
Seafood 📋 36235539Thyroidal and Extrathyroidal Requirements for Iodine and Selenium: A Combined Evolutionary and (Patho)Physiological Approach
Sesamin 📋 37407302Sesamin alleviated fluoride - induced thyroid endocrine disruption in zebrafish (Danio rerio)
Skullcap 📋31636683Therapeutic Effect of Scutellaria baicalensis on L-Thyroxine-Induced Hyperthyroidism Rats
Spirulina 📋31322200Treatment for benign thyroid nodules with a combination of natural extracts
Syringic Acid 📋 34047416Syringic acid, a novel thyroid hormone receptor-β agonist, ameliorates propylthiouracil-induced thyroid toxicity in rats
Tea Polyphenols 📋 36821039Tea Polyphenols Reduce Inflammation of Orbital Fibroblasts in Graves' Ophthalmopathy via the NF-κB/NLRP3 Pathway
Ursolic Acid 📋35786050Ursolic acid inhibits proliferation, migration and invasion of human papillary thyroid carcinoma cells via CXCL12/CXCR4/CXCR7 axis through cancer-associated fibroblasts
Vitamin B1 📋37906392Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase
Vitamin B3 📋7776715Nicotinic Acid Decreases Serum Thyroid Hormone Levels While Maintaining a Euthyroid State
Vitamin B6 📋32218408The Impact of B Vitamins on the Functioning of Methylation Cycle in the Liver and the Kidneys of Hyper- And Hypothyroid Rats
Whey Protein 📋33984891Effects of Regular Whey Protein Consumption on Rat Thyroid Functions
Yam 📋 37600377Integrating network pharmacology and experimental studies for uncovering the molecular mechanisms of Dioscorea bulbifera L. in the treatment of thyroid cancer